mouse KCNE1 shRNA silencing AAV

Name
AAV-m-KCNE1-shRNA

Cat No
shAAV-262619

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Kcne1.

shAAV-262619

AAV-m-KCNE1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Kcne1 (potassium voltage-gated channel, Isk-related subfamily, member 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Isk; MinK; nmf190

Description (Vector)

Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr).

Gene ID

16509

Gene Name (Vector)

potassium voltage-gated channel, Isk-related subfamily, member 1

Gene Symbol

Kcne1

ORF Size (aa)

390

ORF Size (bp)

390 bp

RefSeq ID

NM_008424

RefSeq Synonyms

NM_008424, BC094276,

Species

mouse

UniGene ID

Mm.299425

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.