mouse JTV1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Aimp2.
shAAV-262543
AAV-m-JTV1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Aimp2 (aminoacyl tRNA synthetase complex-interacting multifunctional protein 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AA407136; AA407225; Aimp2(p38); Jtv1
Description (Vector)
Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
Gene ID
231872
Gene Name (Vector)
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
Gene Symbol
Aimp2
ORF Size (aa)
963
RefSeq ID
NM_146165
RefSeq Synonyms
NM_146165, NM_001172146, BC026972, BC026958, BC024480, BC024410,
Species
mouse
UniGene ID
Mm.200499
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.