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mouse IL22RA1 shRNA silencing AAV

Name 
AAV-m-IL22RA1-shRNA
Cat No 
shAAV-262155
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Il22ra1.

shAAV-262155
AAV-m-IL22RA1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Il22ra1 (interleukin 22 receptor, alpha 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
9130219A07Rik; ENSMUSG00000073746; IL-22R; Il22r
Description (Vector)
Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.
Gene ID
230828
Gene Name (Vector)
interleukin 22 receptor, alpha 1
Gene Symbol
Il22ra1
ORF Size (aa)
1746
ORF Size (bp)
1746 bp
RefSeq ID
NM_178257
RefSeq Synonyms
NM_178257, BC140973, BC140972,
Species
mouse
UniGene ID
Mm.261647

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.