mouse HSD17B12 shRNA silencing AAV

Name 
AAV-m-HSD17B12-shRNA
Cat No 
shAAV-261698
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Hsd17b12.

shAAV-261698
AAV-m-HSD17B12-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Hsd17b12 (hydroxysteroid (17-beta) dehydrogenase 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2610510O05Rik; AI172963; KIK-I; Kik1
Description (Vector)
Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in women. Also has 3-ketoacyl-CoA reductase activity, reducing both long chain 3-ketoacyl-CoAs and long chain fatty acyl-CoAs, suggesting a role in long fatty acid elongation.
Gene ID
56348
Gene Name (Vector)
hydroxysteroid (17-beta) dehydrogenase 12
Gene Symbol
Hsd17b12
ORF Size (aa)
939
ORF Size (bp)
939 bp
RefSeq ID
NM_019657
RefSeq Synonyms
NM_019657, BC090659, BC037620,
Species
mouse
UniGene ID
Mm.22505

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.