mouse HSD11B2 shRNA silencing AAV

Name 
AAV-m-HSD11B2-shRNA
Cat No 
shAAV-261692
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Hsd11b2.

shAAV-261692
AAV-m-HSD11B2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Hsd11b2 (hydroxysteroid 11-beta dehydrogenase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
11HSD2
Description (Vector)
Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
Gene ID
15484
Gene Name (Vector)
hydroxysteroid 11-beta dehydrogenase 2
Gene Symbol
Hsd11b2
ORF Size (aa)
1119
ORF Size (bp)
1119 bp
RefSeq ID
NM_008289
RefSeq Synonyms
NM_008289, BC066209, BC014753,
Species
mouse
UniGene ID
Mm.5079

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.