mouse GZMM shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Gzmm.
shAAV-260987
AAV-m-GZMM-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Gzmm (granzyme M (lymphocyte met-ase 1)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Lmet1; MMET-1
Description (Vector)
Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.
Gene ID
16904
Gene Name (Vector)
granzyme M (lymphocyte met-ase 1)
Gene Symbol
Gzmm
ORF Size (aa)
792
ORF Size (bp)
792 bp
RefSeq ID
NM_008504
RefSeq Synonyms
NM_008504, NM_001302499, NM_001302485, BC145578, BC139218, BC139217,
Species
mouse
UniGene ID
Mm.378960
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.