mouse GRIA1 shRNA silencing AAV

Name
AAV-m-GRIA1-shRNA

Cat No
shAAV-260749

Availability
Immediate

This is an AAV expressing shRNA for silencing of Mouse Gria1.

shAAV-260749

AAV-m-GRIA1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Gria1 (glutamate receptor, ionotropic, AMPA1 (alpha 1)). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

2900051M01Rik; Glr-1; Glr1; GluA1; Glur-1; GluR-A; gluR-K1; Glur1; GluRA; HIPA1

Description (Vector)

Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Gene ID

14799

Gene Name (Vector)

glutamate receptor, ionotropic, AMPA1 (alpha 1)

Gene Symbol

Gria1

ORF Size (aa)

2724

ORF Size (bp)

2724 bp

RefSeq ID

NM_008165

RefSeq Synonyms

NM_008165, NM_001252403, NM_001113325, BC056397,

Species

mouse

UniGene ID

Mm.4920

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.