mouse GREM1 shRNA silencing AAV

Cat. No: shAAV-260742

Availability: 4-5 weeks

Name: AAV-m-GREM1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Grem1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Grem1
Gene Name: gremlin 1, DAN family BMP antagonist
Gene ID: 23892
Gene Synonyms: Cktsf1b1; Drm; Grem; ld
ORF Size: 555 bp
RefSeq#: NM_011824
Gene Description: Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Acts as inhibitor of monocyte chemotaxis (By similarity).
UniGene ID: Mm.474483