mouse GREM1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Grem1.
shAAV-260742
AAV-m-GREM1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Grem1 (gremlin 1, DAN family BMP antagonist). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Cktsf1b1; Drm; Grem; ld
Description (Vector)
Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Acts as inhibitor of monocyte chemotaxis (By similarity).
Gene ID
23892
Gene Name (Vector)
gremlin 1, DAN family BMP antagonist
Gene Symbol
Grem1
ORF Size (aa)
555
ORF Size (bp)
555 bp
RefSeq ID
NM_011824
RefSeq Synonyms
NM_011824, BC015293,
Species
mouse
UniGene ID
Mm.474483
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.