mouse GPHN shRNA silencing AAV

Name 
AAV-m-GPHN-shRNA
Cat No 
shAAV-260516
Availability
Immediate
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Gphn.

shAAV-260516
AAV-m-GPHN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Gphn (gephyrin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
5730552E08Rik; AI662856; BC027112; C230040D23; geph; GPH; GPHRYN
Description (Vector)
Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity). Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
Gene ID
268566
Gene Name (Vector)
gephyrin
Gene Symbol
Gphn
ORF Size (aa)
2319
ORF Size (bp)
2319 bp
RefSeq ID
NM_172952
RefSeq Synonyms
NM_172952, NM_145965, BC127058,
Species
mouse
UniGene ID
Mm.453131

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.