mouse GLS2 shRNA silencing AAV

Name 
AAV-m-GLS2-shRNA
Cat No 
shAAV-260210
Availability
Immediate
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Gls2.

shAAV-260210
AAV-m-GLS2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Gls2 (glutaminase 2 (liver, mitochondrial)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A330074B06Rik; AI195532; GA; GLS; Lga
Description (Vector)
Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation.
Gene ID
216456
Gene Name (Vector)
glutaminase 2 (liver, mitochondrial)
Gene Symbol
Gls2
ORF Size (aa)
1809
ORF Size (bp)
1809 bp
RefSeq ID
NM_001033264
RefSeq Synonyms
NM_001285779, NM_001285777, NM_001033264, BC141115,
Species
mouse
UniGene ID
Mm.30102

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.