mouse GCK shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-259983
Availability:
6-8 weeks
Name:
AAV-m-GCK-shRNA
This is an AAV expressing shRNA for silencing of Mouse Gck.
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Product Info
- Knockdown
- shRNA screening service available, please inquire about this service or other options.
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Gck
- Gene Name
- glucokinase
- Gene ID
- 103988
- Gene Synonyms
- Gk; GLK; Gls006; HK4; HKIV; Hlb62; HXKP; MODY2
- ORF Size
- 1398 bp
- RefSeq#
- NM_010292
- Gene Description
- Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage.
- UniGene ID
- Mm.220358
Related Products
Product | Cat No. |
---|---|
AAV-h-GCK | AAV-209742 |
AAV-m-GCK | AAV-259983 |
Ad-h-GCK | ADV-209742 |
Ad-m-GCK | ADV-259983 |
AAV-h-GCK-shRNA | shAAV-209742 |
Ad-h-GCK-shRNA | shADV-209742 |
Ad-m-GCK-shRNA | shADV-259983 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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