mouse BACE2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Bace2.
shAAV-259759
AAV-m-BACE2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Bace2 (beta-site APP-cleaving enzyme 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110059C24Rik; AEPLC; AI850424; ALP56; ARP1; ASP1; ASP21; BAE2; CDA13; CEAP1; DRAP
Description (Vector)
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
Gene ID
56175
Gene Name (Vector)
beta-site APP-cleaving enzyme 2
Gene Symbol
Bace2
ORF Size (aa)
1545
ORF Size (bp)
1545 bp
RefSeq ID
NM_019517
RefSeq Synonyms
NM_019517, BC131947, BC120773,
Species
mouse
UniGene ID
Mm.97885
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.