mouse FRS2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Frs2.
shAAV-259647
AAV-m-FRS2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Frs2 (fibroblast growth factor receptor substrate 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4732458E18; C330018A15Rik; Frs2alpha; SNT1
Description (Vector)
Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
Gene ID
327826
Gene Name (Vector)
fibroblast growth factor receptor substrate 2
Gene Symbol
Frs2
ORF Size (aa)
1527
ORF Size (bp)
1527 bp
RefSeq ID
NM_177798
RefSeq Synonyms
NM_177798, BC055334, BC043109,
Species
mouse
UniGene ID
Mm.135965
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.