mouse FPR2 shRNA silencing AAV

Name 
AAV-m-FPR2-shRNA
Cat No 
shAAV-259618
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Fpr2.

shAAV-259618
AAV-m-FPR2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Fpr2 (formyl peptide receptor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
E330010I07Rik; Fpr-rs2
Description (Vector)
Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).
Gene ID
14289
Gene Name (Vector)
formyl peptide receptor 2
Gene Symbol
Fpr2
ORF Size (aa)
1056
ORF Size (bp)
1056 bp
RefSeq ID
NM_008039
RefSeq Synonyms
NM_008039, BC117066,
Species
mouse
UniGene ID
Mm.477887

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.