mouse FN1 shRNA silencing AAV

Name 
AAV-m-FN1-shRNA
Cat No 
shAAV-259516
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Fn1.

shAAV-259516
AAV-m-FN1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Fn1 (fibronectin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
E330027I09; Fn; Fn-1
Description (Vector)
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape|Function: Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.
Gene ID
14268
Gene Name (Vector)
fibronectin 1
Gene Symbol
Fn1
ORF Size (aa)
6816
ORF Size (bp)
6816 bp
RefSeq ID
NM_010233
RefSeq Synonyms
NM_010233, NM_001276413, NM_001276412, NM_001276411, NM_001276410, NM_001276409, NM_001276408, BC145271, BC138421,
Species
mouse
UniGene ID
Mm.193099

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.