mouse FMR1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Fmr1.
shAAV-259506
AAV-m-FMR1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Fmr1 (fragile X mental retardation syndrome 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Fmr-1; FMRP
Description (Vector)
Translation repressor. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C).
Gene ID
14265
Gene Name (Vector)
fragile X mental retardation syndrome 1
Gene Symbol
Fmr1
ORF Size (aa)
1845
ORF Size (bp)
1845 bp
RefSeq ID
NM_008031
RefSeq Synonyms
NM_008031, NM_001290424, BC079671,
Species
mouse
UniGene ID
Mm.3451
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.