mouse FKBP8 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Fkbp8.
shAAV-259457
AAV-m-FKBP8-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Fkbp8 (FK506 binding protein 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
38kDa; FKBP-38; FKBP-8; Fkbp38
Description (Vector)
Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.
Gene ID
14232
Gene Name (Vector)
FK506 binding protein 8
Gene Symbol
Fkbp8
ORF Size (aa)
1071
ORF Size (bp)
1071 bp
RefSeq ID
NM_010223
RefSeq Synonyms
NM_010223, NM_001199631, NM_001111066, BC027808, BC003739,
Species
mouse
UniGene ID
Mm.141864
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.