mouse FIGLA shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Figla.
shAAV-259427
AAV-m-FIGLA-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Figla (folliculogenesis specific basic helix-loop-helix). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
bHLHc8; FIGalpha
Description (Vector)
Germline specific transcription factor implicated in postnatal oocyte-specific gene expression. Plays a key regulatory role in the expression of multiple oocyte-specific genes, including those that initiate folliculogenesis and those that encode the zona pellucida (ZP1, ZP2 and ZP3) required for fertilization and early embryonic survival. Essential for oocytes to survive and form primordial follicles. The persistence of FIGLA in adult females suggests that it may regulate additional pathways that are essential for normal ovarian development. Binds to the E-box (5'-CANNTG-3') of the ZPs (ZP1, ZP2, ZP3) promoters.
Gene ID
26910
Gene Name (Vector)
folliculogenesis specific basic helix-loop-helix
Gene Symbol
Figla
ORF Size (aa)
585
RefSeq ID
NM_012013
RefSeq Synonyms
NM_012013, BC141606, BC140213,
Species
mouse
UniGene ID
Mm.8024
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.