mouse FGF23 shRNA silencing AAV

Name
AAV-m-FGF23-shRNA

Cat No
shAAV-259372

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Fgf23.

shAAV-259372

AAV-m-FGF23-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Fgf23 (fibroblast growth factor 23). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.

Gene ID

64654

Gene Name (Vector)

fibroblast growth factor 23

Gene Symbol

Fgf23

ORF Size (aa)

756

RefSeq ID

NM_022657

RefSeq Synonyms

NM_022657, BC120605,

Species

mouse

UniGene ID

Mm.347933

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.