mouse FBXL15 shRNA silencing AAV

Name 
AAV-m-FBXL15-shRNA
Cat No 
shAAV-259197
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Fbxl15.

shAAV-259197
AAV-m-FBXL15-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Fbxl15 (F-box and leucine-rich repeat protein 15). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
0710008C12Rik; Fbxo37
Description (Vector)
Substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2.
Gene ID
68431
Gene Name (Vector)
F-box and leucine-rich repeat protein 15
Gene Symbol
Fbxl15
ORF Size (aa)
891
RefSeq ID
NM_133694
RefSeq Synonyms
NM_133694, BC016499,
Species
mouse
UniGene ID
Mm.19973

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.