mouse FBXL15 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Fbxl15.
shAAV-259197
AAV-m-FBXL15-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Fbxl15 (F-box and leucine-rich repeat protein 15). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
0710008C12Rik; Fbxo37
Description (Vector)
Substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2.
Gene ID
68431
Gene Name (Vector)
F-box and leucine-rich repeat protein 15
Gene Symbol
Fbxl15
ORF Size (aa)
891
RefSeq ID
NM_133694
RefSeq Synonyms
NM_133694, BC016499,
Species
mouse
UniGene ID
Mm.19973
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.