mouse EOMES shRNA silencing AAV

Name 
AAV-m-EOMES-shRNA
Cat No 
shAAV-258539
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Eomes.

shAAV-258539
AAV-m-EOMES-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Eomes (eomesodermin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C77258; TBR-2; Tbr2
Description (Vector)
Functions as a transcriptional activator playing a crucial role during development. Functions in trophoblast differentiation and later in gastrulation, regulating both mesoderm delamination and endoderm specification. Plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex. Also involved in the differentiation of CD8+ T-cells during immune response regulating the expression of lytic effector genes.
Gene ID
13813
Gene Name (Vector)
eomesodermin
Gene Symbol
Eomes
ORF Size (aa)
2124
ORF Size (bp)
2124 bp
RefSeq ID
NM_010136
RefSeq Synonyms
NM_010136, NM_001164789, BC094319,
Species
mouse
UniGene ID
Mm.200692

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.