mouse EDEM1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Edem1.
shAAV-257750
AAV-m-EDEM1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Edem1 (ER degradation enhancer, mannosidase alpha-like 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
A130059K23Rik; EDEM; mKIAA0212
Description (Vector)
Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It lacks mannosidase activity.
Gene ID
192193
Gene Name (Vector)
ER degradation enhancer, mannosidase alpha-like 1
Gene Symbol
Edem1
ORF Size (aa)
1959
ORF Size (bp)
1959 bp
RefSeq ID
NM_138677
RefSeq Synonyms
NM_138677, BC023237,
Species
mouse
UniGene ID
Mm.21596
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.