mouse DYRK1A shRNA silencing AAV

Name 
AAV-m-DYRK1A-shRNA
Cat No 
shAAV-257590
Availability
Immediate
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Dyrk1a.

shAAV-257590
AAV-m-DYRK1A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Dyrk1a (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2310043O08Rik; D16Ertd272e; D16Ertd493e; Dyrk; ENSMUSG00000074897; Gm10783; mmb; Mnbh; Mp86
Description (Vector)
DYRK1A may play a role in a signaling pathway regulating nuclear functions of cell proliferation. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates.
Gene ID
13548
Gene Name (Vector)
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a
Gene Symbol
Dyrk1a
ORF Size (aa)
2292
ORF Size (bp)
2292 bp
RefSeq ID
NM_007890
RefSeq Synonyms
NM_007890, NM_001113389, BC145405, BC138716, BC129889, BC129888,
Species
mouse
UniGene ID
Mm.310973

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.