mouse KDM6A shRNA silencing AAV

Name 
AAV-m-KDM6A-shRNA
Cat No 
shAAV-257562
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Kdm6a.

shAAV-257562
AAV-m-KDM6A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Kdm6a (lysine (K)-specific demethylase 6A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Utx
Description (Vector)
Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.
Gene ID
22289
Gene Name (Vector)
lysine (K)-specific demethylase 6A
Gene Symbol
Kdm6a
ORF Size (aa)
4275
ORF Size (bp)
4275 bp
RefSeq ID
NM_009483
RefSeq Synonyms
NM_009483, NM_001310444, BC053433,
Species
mouse
UniGene ID
Mm.257498

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.