mouse DRAP1 shRNA silencing AAV

Name 
AAV-m-DRAP1-shRNA
Cat No 
shAAV-257448
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Drap1.

shAAV-257448
AAV-m-DRAP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Drap1 (Dr1 associated protein 1 (negative cofactor 2 alpha)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2310074H19Rik; NC2-alpha
Description (Vector)
The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own.
Gene ID
66556
Gene Name (Vector)
Dr1 associated protein 1 (negative cofactor 2 alpha)
Gene Symbol
Drap1
ORF Size (aa)
618
RefSeq ID
NM_024176
RefSeq Synonyms
NM_024176, NM_001291080, BC002090,
Species
mouse
UniGene ID
Mm.275446

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.