mouse DOK1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Dok1.
shAAV-257383
AAV-m-DOK1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Dok1 (docking protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AW557123; p62DOK
Description (Vector)
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
Gene ID
13448
Gene Name (Vector)
docking protein 1
Gene Symbol
Dok1
ORF Size (aa)
1449
ORF Size (bp)
1449 bp
RefSeq ID
NM_010070
RefSeq Synonyms
NM_010070, NM_001291799, BC013066,
Species
mouse
UniGene ID
Mm.156
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.