mouse DHCR24 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Dhcr24.
shAAV-257126
AAV-m-DHCR24-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Dhcr24 (24-dehydrocholesterol reductase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2310076D10Rik; 5830417J06Rik; mKIAA0018
Description (Vector)
Catalyzes the reduction of the delta-24 double bond of sterol intermediates. Protects cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress. Also protects against amyloid-beta peptide-induced apoptosis.
Gene ID
74754
Gene Name (Vector)
24-dehydrocholesterol reductase
Gene Symbol
Dhcr24
ORF Size (aa)
1551
ORF Size (bp)
1551 bp
RefSeq ID
NM_053272
RefSeq Synonyms
NM_053272, BC019797,
Species
mouse
UniGene ID
Mm.133370
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.