mouse DAO shRNA silencing AAV

Name 
AAV-m-DAO-shRNA
Cat No 
shAAV-256798
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Dao.

shAAV-256798
AAV-m-DAO-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Dao (D-amino acid oxidase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI987963; DAAO; DAMOX; Dao-1; Dao1
Description (Vector)
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.
Gene ID
13142
Gene Name (Vector)
D-amino acid oxidase
Gene Symbol
Dao
ORF Size (aa)
1038
ORF Size (bp)
1038 bp
RefSeq ID
NM_010018
RefSeq Synonyms
NM_010018, NM_001286397, NM_001286396, BC018377, BC015269,
Species
mouse
UniGene ID
Mm.20115

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.