mouse CYP24A1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Cyp24a1.
shAAV-256471
AAV-m-CYP24A1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Cyp24a1 (cytochrome P450, family 24, subfamily a, polypeptide 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
24-OHase; CP24; Cyp24
Description (Vector)
Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23-hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product.
Gene ID
13081
Gene Name (Vector)
cytochrome P450, family 24, subfamily a, polypeptide 1
Gene Symbol
Cyp24a1
ORF Size (aa)
1545
ORF Size (bp)
1545 bp
RefSeq ID
NM_009996
RefSeq Synonyms
NM_009996, BC109140, BC109139,
Species
mouse
UniGene ID
Mm.6575
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.