mouse CYP1A2 shRNA silencing AAV

Name 
AAV-m-CYP1A2-shRNA
Cat No 
shAAV-256466
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Cyp1a2.

shAAV-256466
AAV-m-CYP1A2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Cyp1a2 (cytochrome P450, family 1, subfamily a, polypeptide 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CP12; Cyp1a1; P450-3
Description (Vector)
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.
Gene ID
13077
Gene Name (Vector)
cytochrome P450, family 1, subfamily a, polypeptide 2
Gene Symbol
Cyp1a2
ORF Size (aa)
1542
ORF Size (bp)
1542 bp
RefSeq ID
NM_009993
RefSeq Synonyms
NM_009993, BC054827, BC018298,
Species
mouse
UniGene ID
Mm.15537

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.