mouse CRK shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Crk.
shAAV-256132
AAV-m-CRK-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Crk (v-crk avian sarcoma virus CT10 oncogene homolog). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
c-Crk; Crk-I; Crk-II; Crk-III; Crk3; CrkIII; Crko; p38
Description (Vector)
The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
Gene ID
12928
Gene Name (Vector)
v-crk avian sarcoma virus CT10 oncogene homolog
Gene Symbol
Crk
ORF Size (aa)
615
RefSeq ID
NM_133656
RefSeq Synonyms
NM_133656, NM_001277221, NM_001277219, BC031149, BC012216,
Species
mouse
UniGene ID
Mm.280125
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.