mouse CLK4 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Clk4.
shAAV-255667
AAV-m-CLK4-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Clk4 (CDC like kinase 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI987988; C85119
Description (Vector)
Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates SRSF1 and SRSF3. Required for the regulation of alternative splicing of MAPT/TAU. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.
Gene ID
12750
Gene Name (Vector)
CDC like kinase 4
Gene Symbol
Clk4
ORF Size (aa)
906
ORF Size (bp)
906 bp
RefSeq ID
NM_007714
RefSeq Synonyms
NM_007714, NM_001304744, BC012675, BC002220,
Species
mouse
UniGene ID
Mm.239354
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.