human CLK4 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CLK4.
shAAV-205473
AAV-h-CLK4-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CLK4 (CDC like kinase 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
CLK4 belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined.
Gene ID
57396
Gene Name (Vector)
CDC like kinase 4
Gene Symbol
CLK4
HGNC ID
HGNC:13659
ORF Size (aa)
1122
ORF Size (bp)
1122 bp
RefSeq ID
NM_020666
RefSeq Synonyms
NM_020666, BC143547, BC136261, BC065732,
Species
human
UniGene ID
Hs.406557
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.