mouse CLCA5 shRNA silencing AAV

Name 
AAV-m-CLCA5-shRNA
Cat No 
shAAV-255562
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Clca2.

shAAV-255562
AAV-m-CLCA5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Clca2 (chloride channel accessory 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
4732440A06; AI586120; Clca5
Description (Vector)
Plays a role in modulating chloride current across the plasma membrane in a calcium-dependent manner, and cell adhesion. Involved in basal cell adhesion and/or stratification of squamous epithelia. May act as a tumor suppressor in breast and colorectal cancer. Plays a key role for cell adhesion in the beginning stages of lung metastasis via the binding to ITGB4.
Gene ID
229933
Gene Name (Vector)
chloride channel accessory 2
Gene Symbol
Clca2
ORF Size (aa)
2829
ORF Size (bp)
2829 bp
RefSeq ID
NM_178697
RefSeq Synonyms
NM_178697, BC096379,
Species
mouse
UniGene ID
Mm.331420

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.