mouse CISD2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Cisd2.
shAAV-255515
AAV-m-CISD2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Cisd2 (CDGSH iron sulfur domain 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1500009M05Rik; 1500026J14Rik; 1500031D15Rik; AI848398; B630006A20Rik; Miner1; Noxp70; Zcd2
Description (Vector)
Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.
Gene ID
67006
Gene Name (Vector)
CDGSH iron sulfur domain 2
Gene Symbol
Cisd2
ORF Size (aa)
408
RefSeq ID
NM_025902
RefSeq Synonyms
NM_025902, BC058279,
Species
mouse
UniGene ID
Mm.269993
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.