mouse CHST2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Chst2.
shAAV-255477
AAV-m-CHST2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Chst2 (carbohydrate sulfotransferase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI428561; AW121776; C130041E03Rik; Chts2; GlcNAc6ST; Gn6st; GST-2
Description (Vector)
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues within keratan-like structures on N-linked glycans and within mucin-associated glycans that can ultimately serve as SELL ligands. SELL ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Participates in biosynthesis of the SELL ligand sialyl 6-sulfo Lewis X and in lymphocyte homing to Peyer patches. Has no activity toward O-linked sugars. Its substrate specificity may be influenced by its subcellular location. Sulfates GlcNAc residues at terminal, non-reducing ends of oligosaccharide chains.
Gene ID
54371
Gene Name (Vector)
carbohydrate sulfotransferase 2
Gene Symbol
Chst2
ORF Size (aa)
1452
ORF Size (bp)
1452 bp
RefSeq ID
NM_018763
RefSeq Synonyms
NM_018763, BC051963,
Species
mouse
UniGene ID
Mm.212446
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.