mouse CHML shRNA silencing AAV

Name 
AAV-m-CHML-shRNA
Cat No 
shAAV-255408
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Chml.

shAAV-255408
AAV-m-CHML-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Chml (choroideremia-like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI450814; E030003F13Rik; REP-2; Rep2
Description (Vector)
Binds unprenylated Rab proteins, presents it to the catalytic Rab GGTase dimer, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than REP-1 in supporting prenylation of Rab3 family.
Gene ID
12663
Gene Name (Vector)
choroideremia-like
Gene Symbol
Chml
ORF Size (aa)
1866
ORF Size (bp)
1866 bp
RefSeq ID
NM_021350
RefSeq Synonyms
NM_021350, BC118932,
Species
mouse
UniGene ID
Mm.440490

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.