mouse CENPA shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Cenpa.
shAAV-255255
AAV-m-CENPA-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Cenpa (centromere protein A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Cenp-A
Description (Vector)
Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro).
Gene ID
12615
Gene Name (Vector)
centromere protein A
Gene Symbol
Cenpa
ORF Size (aa)
405
RefSeq ID
NM_007681
RefSeq Synonyms
NM_007681, NM_001302132, NM_001302131, NM_001302130, NM_001302129, BC011038,
Species
mouse
UniGene ID
Mm.290563
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.