mouse CD48 shRNA silencing AAV

Name 
AAV-m-CD48-shRNA
Cat No 
shAAV-255017
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Cd48.

shAAV-255017
AAV-m-CD48-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Cd48 (CD48 antigen). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI449234;AW610730;BCM1;Bcm-1;BCM1 surface antigen;BLAST;BLAST1;BLAST-1;CD antigen CD48;CD48 antigen;HM48-1;MEM-102;MRC OX-45 surface antigen;Sgp-60;signaling lymphocytic activation molecule 2;SLAM family member 2;SLAMF2
Description (eCommerce)
CD48 is a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. CD48 is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. CD48 does not have a transmembrane domain, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor [taken from NCBI Entrez Gene (Gene ID: 962)].
Description (Vector)
Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation.
Gene ID
12506
Gene Name (eCommerce)
CD48 antigen
Gene Name (Vector)
CD48 antigen
Gene Symbol
Cd48
NCBI Taxonomy ID (eCommerce)
10090.0
ORF Size (aa)
723
Protein Name (eCommerce)
CD48 antigen
RefSeq ID
NM_007649
RefSeq Synonyms
NM_007649, BC060977,
Research Areas (Faceted)
immunology,signal_transduction
Species
mouse
Target Sentence
CD48 is a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. CD48 is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. CD48 does not have a transmembrane domain, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor [taken from NCBI Entrez Gene (Gene ID: 962)].
UniGene ID
Mm.1738
UniProt ID (eCommerce)
P18181

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.