mouse CD36 shRNA silencing AAV

Name 
AAV-m-CD36-shRNA
Cat No 
shAAV-255002
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Cd36.

shAAV-255002
AAV-m-CD36-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Cd36 (CD36 antigen). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD antigen CD36;CD36 antigen;FAT;fatty acid translocase;glycoprotein IIIb;GPIIIB;GPIV;PAS IV;PAS-4;platelet glycoprotein 4;platelet glycoprotein IV;Scarb3
Description (eCommerce)
CD36 is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, CD36 has a variety of functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. [taken from NCBI Entrez Gene (Gene ID: 948)].
Description (Vector)
Seems to have numerous potential physiological functions. Binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Receptor for thombospondins, THBS1 AND THBS2, mediating their antiangiogenic effects.
Gene ID
12491
Gene Name (eCommerce)
CD36 molecule
Gene Name (Vector)
CD36 antigen
Gene Symbol
Cd36
NCBI Taxonomy ID (eCommerce)
10090.0
ORF Size (aa)
1419
ORF Size (bp)
1419 bp
Protein Name (eCommerce)
Platelet glycoprotein 4
RefSeq ID
NM_007643
RefSeq Synonyms
NM_007643, NM_001159558, NM_001159557, NM_001159556, NM_001159555, BC010262,
Research Areas (Faceted)
infectious_disease,signal_transduction
Species
mouse
Target Sentence
CD36 is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, CD36 has a variety of functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. [taken from NCBI Entrez Gene (Gene ID: 948)].
UniGene ID
Mm.406799
UniProt ID (eCommerce)
Q08857

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.