mouse CD19 shRNA silencing AAV

Name 
AAV-m-CD19-shRNA
Cat No 
shAAV-254948
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Cd19.

shAAV-254948
AAV-m-CD19-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Cd19 (CD19 antigen). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AW495831; B-lymphocyte antigen CD19; CD antigen CD19; differentiation antigen CD19
Description (eCommerce)
Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. CD19 encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulatio [taken from NCBI Entrez Gene (Gene ID: 930)].
Description (Vector)
Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
Gene ID
12478
Gene Name (eCommerce)
CD19 antigen
Gene Name (Vector)
CD19 antigen
Gene Symbol
Cd19
NCBI Taxonomy ID (eCommerce)
10090.0
ORF Size (aa)
1644
ORF Size (bp)
1644 bp
Protein Name (eCommerce)
B-lymphocyte antigen CD19
RefSeq ID
NM_009844
RefSeq Synonyms
NM_009844, BC156767,
Research Areas
B-cell Receptor Signaling,Cancer,EGFR Signaling,EGFR Signaling in Cancer,Fc Receptor Signaling,FGF Signaling,Host-Virus Interactions,Immune Cells and Tumor Markers,Immunology,Immuno-Oncology,Innate Immunity,Neurobiology,NGF Signaling,PDGF Signaling,PI3K/Akt Signaling,PI3K-AKT Signaling in Cancer,SCF-KIT Signaling,Signal Transduction
Research Areas (Faceted)
cancer,immuno_oncology,immunology,infectious_disease,neurobiology,signal_transduction,stem_cell_biology
Species
mouse
Target Sentence
Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. CD19 encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulatio [taken from NCBI Entrez Gene (Gene ID: 930)].
UniGene ID
Mm.4360
UniProt ID (eCommerce)
P25918

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.