mouse CBX4 shRNA silencing AAV

Name 
AAV-m-CBX4-shRNA
Cat No 
shAAV-254636
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Cbx4.

shAAV-254636
AAV-m-CBX4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Cbx4 (chromobox 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MPc2; PC2
Description (Vector)
E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I|Function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Gene ID
12418
Gene Name (Vector)
chromobox 4
Gene Symbol
Cbx4
ORF Size (aa)
1458
ORF Size (bp)
1458 bp
RefSeq ID
NM_007625
RefSeq Synonyms
NM_007625, BC117802, BC117801,
Species
mouse
UniGene ID
Mm.471550

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.