mouse CAV2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Cav2.
shAAV-254588
AAV-m-CAV2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Cav2 (caveolin 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI447843
Description (Vector)
CAV2 may act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity).
Gene ID
12390
Gene Name (Vector)
caveolin 2
Gene Symbol
Cav2
ORF Size (aa)
489
ORF Size (bp)
489 bp
RefSeq ID
NM_016900
RefSeq Synonyms
NM_016900, NM_001277756, BC023095,
Species
mouse
UniGene ID
Mm.396075
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.