mouse CAV1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Cav1.
shAAV-254587
AAV-m-CAV1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Cav1 (caveolin 1, caveolae protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Cav; Cav-1
Description (Vector)
CAV1 may act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
Gene ID
12389
Gene Name (Vector)
caveolin 1, caveolae protein
Gene Symbol
Cav1
ORF Size (aa)
537
ORF Size (bp)
537 bp
RefSeq ID
NM_007616
RefSeq Synonyms
NM_007616, NM_001243064, BC052859, BC038280,
Species
mouse
UniGene ID
Mm.470537
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.