mouse CAV1 shRNA silencing AAV

Cat. No: shAAV-254587

Availability: 4-5 weeks

Name: AAV-m-CAV1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Cav1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Cav1
Gene Name: caveolin 1, caveolae protein
Gene ID: 12389
Gene Synonyms: Cav; Cav-1
ORF Size: 537 bp
RefSeq#: NM_007616
Gene Description: CAV1 may act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
UniGene ID: Mm.470537