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mouse CDC42BPA shRNA silencing AAV

Name 
AAV-m-CDC42BPA-shRNA
Cat No 
shAAV-254344
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Cdc42bpa.

shAAV-254344
AAV-m-CDC42BPA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Cdc42bpa (CDC42 binding protein kinase alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A930014J19Rik; DMPK-like
Description (Vector)
Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates: PPP1R12A, LIMK1 and LIMK2. May play a role in TFRC-mediated iron uptake.
Gene ID
226751
Gene Name (Vector)
CDC42 binding protein kinase alpha
Gene Symbol
Cdc42bpa
ORF Size (aa)
5160
ORF Size (bp)
5160 bp
RefSeq ID
NM_001033285
RefSeq Synonyms
NM_001346805, NM_001346804, NM_001033285, BC158095, BC158017,
Species
mouse
UniGene ID
Mm.259655

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.