mouse C8G shRNA silencing AAV

Name 
AAV-m-C8G-shRNA
Cat No 
shAAV-254337
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse C8g.

shAAV-254337
AAV-m-C8G-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse C8g (complement component 8, gamma polypeptide). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol.
Gene ID
69379
Gene Name (Vector)
complement component 8, gamma polypeptide
Gene Symbol
C8g
ORF Size (aa)
609
ORF Size (bp)
609 bp
RefSeq ID
NM_027062
RefSeq Synonyms
NM_027062, NM_001271777, BC019967,
Species
mouse
UniGene ID
Mm.24596

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.