mouse C230052I12RIK shRNA silencing AAV

Name 
AAV-m-C230052I12RIK-shRNA
Cat No 
shAAV-254249
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Faap24.

shAAV-254249
AAV-m-C230052I12RIK-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Faap24 (Fanconi anemia core complex associated protein 24). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AW124591; AW538696; C230052I12Rik
Description (Vector)
Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA.
Gene ID
101831
Gene Name (Vector)
Fanconi anemia core complex associated protein 24
Gene Symbol
Faap24
ORF Size (aa)
666
RefSeq ID
NM_178643
RefSeq Synonyms
NM_178643, BC096687,
Species
mouse
UniGene ID
Mm.389855

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.