mouse ARAP3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Arap3.
shAAV-252889
AAV-m-ARAP3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Arap3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Centd3; cnt-d3; Drag1; E030006K04Rik
Description (Vector)
Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin.
Gene ID
106952
Gene Name (Vector)
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Gene Symbol
Arap3
ORF Size (aa)
4617
ORF Size (bp)
4617 bp
RefSeq ID
NM_139206
RefSeq Synonyms
NM_139206, NM_001205336, BC068145,
Species
mouse
UniGene ID
Mm.247642
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.