mouse AQR shRNA silencing AAV

Name
AAV-m-AQR-shRNA

Cat No
shAAV-252884

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Aqr.

shAAV-252884

AAV-m-AQR-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Aqr (aquarius). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AW495846; mKIAA0560

Description (Vector)

Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.

Gene ID

11834

Gene Name (Vector)

aquarius

Gene Symbol

Aqr

ORF Size (aa)

4446

ORF Size (bp)

4446 bp

RefSeq ID

NM_009702

RefSeq Synonyms

NM_009702, NM_001290788, BC042479,

Species

mouse

UniGene ID

Mm.2545

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.