mouse APLP2 shRNA silencing AAV

Name 
AAV-m-APLP2-shRNA
Cat No 
shAAV-252826
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Aplp2.

shAAV-252826
AAV-m-APLP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Aplp2 (amyloid beta (A4) precursor-like protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI790698; APLP-2
Description (Vector)
APLP2 may play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity).
Gene ID
11804
Gene Name (Vector)
amyloid beta (A4) precursor-like protein 2
Gene Symbol
Aplp2
ORF Size (aa)
2124
ORF Size (bp)
2124 bp
RefSeq ID
NM_009691
RefSeq Synonyms
NM_009691, NM_001102456, NM_001102455, BC052396, BC051999,
Species
mouse
UniGene ID
Mm.19133

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.